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Splitting a dose is necessary whenever the required volume exceeds what a single syringe can hold
Lancet 2009;374:1606-1616 Erratum in: Lancet 2010;375:984
)
Bruising and its effect on absorption Bruising at the injection site is mostly cosmetic, but large bruises can trap medication in the tissue, slowing absorption
Postgrad Med (2010) 122:14557
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